Bright Light's Influence on Hyperactivity: Implications for Hippocampal Processing

old_uid4824
titleBright Light's Influence on Hyperactivity: Implications for Hippocampal Processing
start_date2008/05/16
schedule14h
onlineno
location_infoBât. Fernbach, salle J.-P. Aubert
detailsInvit. Uwe Maskos, umaskos@pasteur.fr, 01 45 68 88 06
summaryRats with dorsal hippocampal (DH) lesions sometimes display hyperactivity, which is expressed by increased locomotion compared to controls.  This hyperactivity effect has been suggested to reflect deficits in behavioral inhibition, anxiety, and spatial-contextual processing.  To examine the relationship between hyperactivity and hippocampal processing, I developed a procedure that challenges rats with the sudden onset of bright light in an open field situation.  During this procedure, DH lesion rats displayed hyperactivity in darkness, but not after the onset of bright light.  In this seminar I will discuss how these results both (a) support the contextual processing view of hippocampus function and (b) underscore the capacity for bright illumination to increase fear motivation and alter exploratory patterns.
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